This review provides practitioners with a review and update on effective practices and evidence in the field of MHPSS. It was first drafted in 2015, presenting evidence and practice specific to children in order to support the implementation of MHPSS activities in humanitarian settings. This updated 2020 Review includes recent evidence updates (2015-2020), and addressing an identified gap in the 2015 Review, includes additional evidence on child and community participation. It serves as a compilation of evidence and best practice around MHPSS for children in humanitarian settings and complements the UNICEF Guidelines on Community-Based Mental Health and Psychosocial Support in Humanitarian Settings and Compendium of resources, a supporting document to UNICEF’s operational guidelines.