Risk communications and community engagement (RCCE) are essential tools to ensure that people are aware of the dangers posed by COVID-19 to themselves and their families, and ensure their involvement in national and local efforts to stop the spread of the virus as well as minimize disruptions to their lives and livelihoods. But in order for RCCE efforts to be effective, they need to be gender-responsive and include all segments of societies, particularly the most of vulnerable and marginalized social groups. These guidelines explain the vulnerabilities of different social groups to COVID-19, and how to address these vulnerabilities in RCCE efforts and plans.